4-Hydroxyhexan-3-one → 5,6-Diethyl-2,3-dihydro-2-propoxymethyl-1,4-dithiin

Participants

Reaction Steps

The method of Example 4 was followed, using propioin (4-hydroxy-3-hexanone) (11.6 g) and 3-propoxypropane-1,2-dithiol (16.6 g) to give 5,6-diethyl-2,3-dihydro-2-propoxymethyl-1,4-dithiin as a greenish oil, b.p. 110°-111.5°/0.2 mm, yield 42%. N.M.R. (CDCl3) 0.8-1.25 δ triplets), 1.6-1.95 δ (complex overlapping signals), 2.75-3.65 δ (complex overlapping signals).

Provenance & Evidence