Methyl phosphonic dichloride → 1-methyl-2-phenyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide

HRID 2058883Notes

Reaction equation

HRID 2058883 reaction equation
[CH2:1]([NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:15][P:16](Cl)(Cl)=[O:17]>>[CH3:15][P:16]1(=[O:17])[C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[CH2:1][N:8]1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 12671Methyl phosphonic dichlorideHCID 66028Benzylaniline

Product 1

HCID 127227031-methyl-2-phenyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxideYield 1.75%

Procedure

The procedure of Example 1 was employed utilizing N-benzylaniline and methyl phosphonic dichloride. The crude product produced as a result of the chromatographic separation yielded without additional purification 1-methyl-2-phenyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide (0.4 g, 1.75% yield) as a brown glass.

Workup

  1. customThe crude product produced as
  2. customa result of the chromatographic separation

Sources & evidence

ORD record
ord-01468e23bed945698a1c0ea2e0ad7a3c
Source dataset
uspto-grants-1982_03
Patent number
US04319913

Reaction notes

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