1-isopropyl-2-trimethylsilyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide → 1-isopropyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide
Reaction equation
[CH:1]([P:4]1(=[O:17])[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[CH2:6][N:5]1[Si](C)(C)C)([CH3:3])[CH3:2]>CO>[CH:1]([P:4]1(=[O:17])[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[CH2:6][NH:5]1)([CH3:3])[CH3:2]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
The 1-isopropyl-2-trimethylsilyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide was added to 50 ml. of methanol and allowed to stand for 40 hours. The methanol was removed under vacuum and the resulting residue was slurried in ether to yield 1-isopropyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide as a white solid. A second crop was obtained to give a total yield of 2.35 g (20% yield) of 1-isopropyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide having a melting point of 149°-151° C. and the following analysis:
Workup
- customThe methanol was removed under vacuum
Sources & evidence
- ORD record
- ord-4ab7571b684a43d2864cbf25f6dd8b7f
- Source dataset
- uspto-grants-1982_03
- Patent number
- US04319913
Reaction notes
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