反应详情

The procedure of Example 36 was employed utilizing N-methyl-N-benzylamine and phenyl phosphonic dichloride. The reaction of the dilithio compound and the phenyl phosphonic dichloride was conducted at -60° C. The residue produced as a result of the distillation process was slurried in ether to yield 1-phenyl-2-methyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide as a white solid. A second crop was obtained and the combined product yield was recrystallized from carbon tetrachloride and petroleum ether to yield 1-phenyl-2-methyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide (2.25 g, 15% yield) having a melting point of 129°-130° C. and the following analysis:

1. customwas conducted at -60° C
2. customThe residue produced as
3. customa result of the distillation process