Benzylaniline → 1-(3-fluorophenyl)-2-phenyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide

HRID 2058916Notes

Reaction equation

HRID 2058916 reaction equation
[CH2:1]([NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:15][C:16]1[CH:17]=[C:18]([P:22](Cl)(Cl)=[O:23])[CH:19]=[CH:20][CH:21]=1>>[F:15][C:16]1[CH:17]=[C:18]([P:22]2(=[O:23])[C:3]3[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=3[CH2:1][N:8]2[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH:19]=[CH:20][CH:21]=1

Participants

3

Reactant 2

HCID 66028BenzylanilineHCID 126706313-Fluorophenyl phosphonic dichloride

Product 1

HCID 130375171-(3-fluorophenyl)-2-phenyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxideYield 13%

Procedure

The procedure of Example 38 was employed utilizing N-benzylaniline and 3-fluorophenyl phosphonic dichloride to yield 1-(3-fluorophenyl)-2-phenyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide (1.3 g, 13% yield) as a white solid having a melting point of 209°-210° C. and the following analysis:

Sources & evidence

ORD record
ord-ba5fd69d2fd242569a9f1ff62c33c56a
Source dataset
uspto-grants-1982_03
Patent number
US04319913

Reaction notes

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