Butylamine → HCID 178449863, compound

HRID 2058941Notes

Reaction equation

HRID 2058941 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:23])[C:9](=[C:12]1[NH:16][C:15]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:14][S:13]1)[C:10]#[N:11].[CH2:24]([NH2:28])[CH2:25][CH2:26][CH3:27]>O1CCOCC1>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]([O-:23])=[C:9]([C:10]#[N:11])[C:12]1[S:13][CH:14]=[C:15]([C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)[N:16]=1.[CH2:24]([NH3+:28])[CH2:25][CH2:26][CH3:27]

Participants

4

Reactant 2

HCID 8007ButylamineHCID 178511149HCID 178511149, compound

Product 1

HCID 178449863HCID 178449863, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

10.17 g (0.03 mol) of 3-(2-chlorophenyl)-3-oxo-2-(4-phenyl-2,3-dihydrothiazole-2-ylidene)-propionitrile were suspended in 15 ml dioxane and were reacted at 25° C. with 2.19 g (0.03 mol) n-butylamine. After short stirring a solution was formed. The solution was then concentrated in a vacuum and the residue was treated with a small amount of a cyclohexane-chloroform mixture. The crystals were removed by suction and digested with hot diisopropylether.

Workup

  1. customwas formed
  2. concentrationThe solution was then concentrated in a vacuum
  3. additionthe residue was treated with a small amount of a cyclohexane-chloroform mixture
  4. customThe crystals were removed by suction

Sources & evidence

ORD record
ord-2bfaebcf69824f8da4f2698deea7910e
Source dataset
uspto-grants-1982_03
Patent number
US04320125

Reaction notes

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