Thionyl Chloride → HCID 12833906, compound

Participants

Reaction Steps

To a solution of 10 g of o-(trifluoromethanesulfonamido)phenylacetic acid in 100 ml of chloroform, there were dropwise added 8.4 g of thionyl chloride. After completion of the addition, the resultant mixture was heated and refluxed until the evolution of the gas stopped. Concentration of the reaction mixture gave a solid substance, which was recrystallized from toluene to give 7.6 g of o-(trifluoromethanesulfonamido)phenylacetyl chloride. M.P. 94°-95° C.

Provenance & Evidence