Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 3-Pyridinecarbonyl chloride, hydrochloride (1:1) | HCID 88438 | — |
| Reactant | HCID 12505087 | HCID 12505087 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 14126411 | HCID 14126411 | — |
Reaction Steps
11 g (50 mmol) of p-cyclohexylacetylphenol and 9.6 g (54 mmol) of nicotinic acid chloride hydrochloride was mixed with 160 ml of dry pyridine and stirred for 8 hours at 40° C. Subsequently, water (66 ml) was added drop by drop until the solution was turbid. The solution was placed in the ice bath, the precipitate sucked off, freed from pyridine by washing with water and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04321268 |
|---|
| Source dataset | uspto-grants-1982_03 |
|---|
| ORD ID | ord-0278188e5b3948919029e76d8a35113c |
|---|
| Source note | uspto-grants-1982_03 |
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