HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Difluorobenzoyl isocyanate → HCID 19072914, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Difluorobenzoyl isocyanate | HCID 2733369 | — |
| Reactant | 4-Ethynylaniline | HCID 3760025 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 19072914 | HCID 19072914 | — |
Reaction Steps
With stirring, 3.2 g of 2,6-difluorobenzoylisocyanate are added dropwise to a ready prepared mixture of 2 g of 4-aminophenylacetylene in 20 ml of absolute ether. The precipitate is filtered with suction after 2 hours and recrystallised from ethanol, yielding N-(4-ethynylphenyl)-N'-(2,6-difluorobenzoyl)urea with a melting point of 213°-217° C. (Compound 1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04321276 |
| Source dataset | uspto-grants-1982_03 |
| ORD ID | ord-791bc6ae57774321aadadfbc6fc3a6e7 |
| Source note | uspto-grants-1982_03 |