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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 205903Generated: October 31, 2026

Methanol → 3-(2-Chloro-4-ethynyl-phenylamino)-N-(2,3-dihydroxy-propoxy)isonicotinamide

https://huagongshe.com/reaction/205903

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantDimethylformamideHCID 6228—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantTrimethylsilylacetyleneHCID 66111—
ReactantHCID 178523989HCID 178523989—
Product3-(2-Chloro-4-ethynyl-phenylamino)-N-(2,3-dihydroxy-propoxy)isonicotinamideHCID 11610213—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-62a8007391294d5080dc014128d65267
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)