反应详情

17.5 parts of 2-oxo-4-iminothiazolidine and 32 parts of the adduct of 1,3-diiminoisoindoline and ethylene glycol, in 400 parts of methanol, are refluxed for 5 hours. After the mixture has cooled, the product is filtered off, washed with methanol and dried. 33 parts of 1-imino-3-(2'-oxo-4'-iminothiazolidinylidene)-isoindoline (formula II, Z=°O) are obtained as a yellowish brown powder.

1. temperatureAfter the mixture has cooled
2. filtrationthe product is filtered off
3. washwashed with methanol
4. customdried