Ethylene Glycol → HCID 178509023, compound

HRID 2059069Notes

Reaction equation

HRID 2059069 reaction equation
[O:1]=[C:2]1[NH:6][C:5](=[NH:7])[CH2:4][S:3]1.[NH:8]=[C:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11](=N)[NH:10]1.C(O)CO>CO>[NH:8]=[C:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11](=[C:4]2[S:3][C:2](=[O:1])[NH:6][C:5]2=[NH:7])[NH:10]1

Participants

5

Reactant 3

HCID 174Ethylene GlycolHCID 1373471612(5H)-Thiazolone, 4-amino-HCID 178508669HCID 178508669, compound

Product 1

HCID 178509023HCID 178509023, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

17.5 parts of 2-oxo-4-iminothiazolidine and 32 parts of the adduct of 1,3-diiminoisoindoline and ethylene glycol, in 400 parts of methanol, are refluxed for 5 hours. After the mixture has cooled, the product is filtered off, washed with methanol and dried. 33 parts of 1-imino-3-(2'-oxo-4'-iminothiazolidinylidene)-isoindoline (formula II, Z=°O) are obtained as a yellowish brown powder.

Workup

  1. temperatureAfter the mixture has cooled
  2. filtrationthe product is filtered off
  3. washwashed with methanol
  4. customdried

Sources & evidence

ORD record
ord-35ea67bd51284c1f9b36af32db24f4d1
Source dataset
uspto-grants-1982_03
Patent number
US04321390

Reaction notes

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