HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 86738303, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Cyclopropanecarbonyl chloride | HCID 77637 | — |
| Reactant | HCID 21726051 | HCID 21726051 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 86738303 | HCID 86738303 | — |
Reaction Steps
There were slowly added 6 ml of cyclopropanecarboxylic acid chloride to an iced solution of 15 g of 8β-methoxycarbonylergoline in 170 ml of pyridine. The reaction mixture was left at room temperature for 1 hr, then poured into cooled acid water. The precipitate was filtered and crystallized from methanol to give 16 g of 6-cyclopropanoyl-8β-methoxycarbonylergoline melting at 276°-278° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04321381 |
| Source dataset | uspto-grants-1982_03 |
| ORD ID | ord-ae5cf1901b744dc79ecd041dfee7cc84 |
| Source note | uspto-grants-1982_03 |