m-Toluidine → HCID 20450372, compound

Participants

Reaction Conditions

Reaction Steps

4.0 g of 4,6-dichloroquinazoline were dissolved in 50 ml of dioxan and then 2.0 g of m-toluidine were added. The mixture was then heated to reflux for 3 hours at 100° C. After completion of the reaction, the precipitated product was collected by filtration and recrystallized from ethanol to afford 3.7 g (yield 60%) of the desired Compound No. 4, in the form of pale yellow needles melting at 251°-254° C. (with decomposition).

Provenance & Evidence