HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Hydroxybenzonitrile → HCID 4227476, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Hydroxybenzonitrile | HCID 11907 | — |
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 4227476 | HCID 4227476 | — |
Reaction Steps
2-Hydroxybenzonitrile (10 grams), hydroxylamine HCl (7 g.) in 150 ml. methanol, and sodium methoxide (9.0 grams) were refluxed for about 18 hours. The reaction mixture was then filtered and the ethanol evaporated. Next water was added and the product extracted into ethyl acetate. Drying and evaporation of the solvent left an oily product which solidified upon standing. The identity of the final product was confirmed by NMR and IR analysis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04322429 |
| Source dataset | uspto-grants-1982_03 |
| ORD ID | ord-18582634f3a04418a5f6dabb6deb9d85 |
| Source note | uspto-grants-1982_03 |