HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 20545924, compound → HCID 20545907, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 20545924 | HCID 20545924 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 20545907 | HCID 20545907 | — |
Reaction Steps
A solution of 4-(4-chlorophenyl)-2,2-dimethyl-7-(2-dimethylaminoethoxy)-1-methylidene tetralin hydrochloride (4 g) in ethanol (150 ml) was hydrogenated in the presence of 10% palladium on charcoal (0.4 g) until hydrogen uptake was complete. After filtration the solvent was removed in vacuo to give 4-(4-chlorophenyl)-1,2,2-trimethyl-7-(2-dimethylaminoethoxy)tetralin hydrochloride. Recrystallisation from ethanol-ether gave white prisms, m.p. 173°-6° (3.6 g, 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04322370 |
| Source dataset | uspto-grants-1982_03 |
| ORD ID | ord-ae5e662475a7482c82e89ae0efc84aef |
| Source note | uspto-grants-1982_03 |