HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 20545901, compound → HCID 20545922, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 20545901 | HCID 20545901 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 20545922 | HCID 20545922 | — |
Reaction Steps
A solution of 4-(4-chlorophenyl)-7-(2-benzylmethylaminoethoxy)-2,2-dimethyl-1-tetralone hydrochloride (4.3 g) in ethanol (100 ml) was hydrogenated in the presence of 10% palladium on charcoal (0.43 g) until hydrogen uptake was complete. After filtration the solvent was removed in vacuo to give 4-(4-chlorophenyl)-2,2-dimethyl-7-(2-methylaminoethoxy)-1-tetralone hydrochloride. Recrystallisation from ether-ethyl acetate gave white crystals m.p. 150°-3° (2.6 g, 74%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04322370 |
| Source dataset | uspto-grants-1982_03 |
| ORD ID | ord-31a11d4009d444bdbea551316fa06efc |
| Source note | uspto-grants-1982_03 |