Potassium tert-butoxide → HCID 20547141, compound

HRID 2059336Notes

Reaction equation

HRID 2059336 reaction equation
C(=[C:5]1[CH:10]=[CH:9][CH:8]=[N:7][CH:6]1[CH2:11][NH2:12])C(C)C.[CH3:13][C:14]([O-])([CH3:16])[CH3:15].[K+]>C1(C)C=CC=CC=1>[N:7]1[CH:8]=[CH:9][CH:10]=[CH:5][C:6]=1[CH:11]=[N:12][CH2:13][CH:14]([CH3:16])[CH3:15]

Participants

4

Reactant 2

HCID 23665647Potassium tert-butoxideHCID 70543438HCID 70543438, compound

Product 1

HCID 20547141HCID 20547141, compoundYield 1,583.3%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

The procedure is carried out as described in Example 1 (b) but with the use of 138 g (0.85 mol) of isobutylidene-2-aminomethylpyridine, 150 ml of toluene and 4 g (0.036 mol) of potassium tert-butylate. After a reaction time of 30 minutes at 40° C. and subsequent distillation, there is obtained 92 g (0.57 mol) of 2-pyridylmethylidene-isobutylamine; yield 67% of theory; b.p. 95° C./2.0×103Pa.

Workup

  1. distillationAfter a reaction time of 30 minutes at 40° C. and subsequent distillation

Sources & evidence

ORD record
ord-835489086c7349d8b7ada8110dce64d2
Source dataset
uspto-grants-1982_03
Patent number
US04322536

Reaction notes

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