Potassium Iodide → HCID 20547117, compound

Participants

Reaction Steps

A mixture of 19.9 g (0.05 mole) of 1,3-bis-(2,2,6,6-tetramethylpiperid-4-yl)-2-methyl-2-oxo-1,3,2-diazaphospholane (compound 1), 16.6 g of potassium carbonate, 0.3 g of finely powdered potassium iodide, 24.2 g of allyl bromide and 80 ml of ethyl methyl ketone is stirred for 18 hours at reflux temperature. The mixture is then filtered, the filtrate is freed from the solvent in vacuo and the residual crystalline crude product is recrystallised from acetonitrile, yielding pure 1,3-bis(1-allyl-2,2,6,6-tetramethylpiperid-4-yl)-2-methyl-2-oxo-1,3,2-diazaphospholane (compound 13) with a melting point of 168°-169° C.

Provenance & Evidence