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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2059414Generated: November 1, 2026

4-Methoxybenzaldehyde → ethyl (E)-3-(4-methoxyphenyl)-2-methylprop-2-enoate

https://huagongshe.com/reaction/2059414

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethoxybenzaldehydeHCID 31244—
Reactant2-Methyl-malonic acid monoethyl esterHCID 295972—
Reagent4-(Dimethylamino)pyridineHCID 14284—
CatalystBenzenemethanamine, trifluoroacetateHCID 12484433—
SolventTolueneHCID 1140—
Productethyl (E)-3-(4-methoxyphenyl)-2-methylprop-2-enoateHCID 110422477%

Reaction Conditions

Temperature50 °C

Provenance & Evidence

DOI10.26434/chemrxiv.15001213
Source datasetTransfer learning optimization of 26 decarboxylative olefination reactions
ORD IDord-f7814de4a6dc470c8fdac92d6e8f1243
Source noteTransfer learning optimization of 26 decarboxylative olefination reactions