4-Chloro-3,5-dinitrobenzotrifluoride → HCID 59293622, compound

HRID 2059778Notes

Reaction equation

HRID 2059778 reaction equation
[OH:1][C@@H:2]1[CH2:6][CH2:5][N:4]([C:7]([OH:9])=[O:8])[CH2:3]1.Cl[C:11]1[C:16]([N+:17]([O-:19])=[O:18])=[CH:15][C:14]([C:20]([F:23])([F:22])[F:21])=[CH:13][C:12]=1[N+:24]([O-:26])=[O:25]>>[C:14]([O:8][C:7]([N:4]1[CH2:5][CH2:6][C@@H:2]([O:1][C:11]2[C:16]([N+:17]([O-:19])=[O:18])=[CH:15][C:14]([C:20]([F:23])([F:22])[F:21])=[CH:13][C:12]=2[N+:24]([O-:26])=[O:25])[CH2:3]1)=[O:9])([CH3:20])([CH3:15])[CH3:13]

Participants

3

Reactant 2

HCID 98094-Chloro-3,5-dinitrobenzotrifluorideHCID 54535200HCID 54535200, compound

Product 1

HCID 59293622HCID 59293622, compound

Procedure

deprotonating (R)-3-Hydroxypyrrolidine-1-carboxylic acid tent-butyl ester, and reacting the resultant compound with 2-chloro-1,3-dinitro-5-trifluoromethylbenzene to form (R)-3-(2,6-dinitro-4-trifluoromethylphenoxy)pyrrolidine-1-carboxylic acid tert-butyl ester;

Sources & evidence

ORD record
ord-68dd21aeb45144ba86ab75fe416dc536
Source dataset
uspto-grants-2012_10
Patent number
US08278309B2

Reaction notes

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