反应详情

26.0 g (70.3 mmol) (1-benzylpiperidin-4-yl)-[2-(5-methoxy-2-nitrophenyl)-ethyl]-amine were hydrogenated with 5.00 g (2.45 mmol) rhodium charcoal (5%, moistened with water) in 350 mL methanol in a 3 bar hydrogen atmosphere for 3 h at RT. The catalyst was removed by suction filtering and the solution was concentrated by rotary evaporation. The residue was immediately further reacted without any further purification.

1. customThe catalyst was removed by suction
2. filtrationfiltering
3. concentrationthe solution was concentrated by rotary evaporation
4. customThe residue was immediately further reacted without any further purification