反应详情

At 170° C. 3.0 g (20 mmol) 5-fluoroindolinone were stirred in 10 mL (98 mmol) acetic anhydride for 3 h. After cooling to RT the mixture was poured onto 200 mL ice water, the precipitated substance was suction filtered and washed with 100 mL water. The solid was recrystallised from water and ethanol. The precipitated product was suction filtered, washed with water and dried i. vac.

1. customAt 170° C
2. filtrationfiltered
3. washwashed with 100 mL water
4. customThe solid was recrystallised from water and ethanol
5. filtrationfiltered
6. washwashed with water
7. customdried i