Sodium Hydroxide → HCID 12348999, compound

HRID 2060074Notes

Reaction equation

HRID 2060074 reaction equation
Cl.[CH3:2][N:3]([CH2:5][CH:6]1[CH2:15][CH2:14][C:13]2[C:8](=[CH:9][CH:10]=[CH:11][C:12]=2[O:16][CH3:17])[C:7]1=[O:18])[CH3:4].[OH-].[Na+]>O>[CH3:4][N:3]([CH2:5][CH:6]1[CH2:15][CH2:14][C:13]2[C:8](=[CH:9][CH:10]=[CH:11][C:12]=2[O:16][CH3:17])[C:7]1=[O:18])[CH3:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 12349000HCID 12349000, compound

Product 1

HCID 12348999HCID 12348999, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

16 g of the product from step 1 were dissolved in water; the solution was adjusted to pH 12 with 32% sodium hydroxide solution, while cooling with ice, and extracted three times with dichloromethane, and the combined organic phases were dried over magnesium sulfate, filtered and concentrated in vacuo.

Workup

  1. temperaturewhile cooling with ice
  2. extractionextracted three times with dichloromethane
  3. dry with materialthe combined organic phases were dried over magnesium sulfate
  4. filtrationfiltered
  5. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-07f4731d981249b283cd0fb56bc0f7d7
Source dataset
uspto-grants-2012_10
Patent number
US08278338B2

Reaction notes

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