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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2060233Generated: October 31, 2026

4-Chlorobenzoyl chloride → 1-(4-Chloro-benzoyl)-pyrrolidine-3-carboxylic acid ethyl ester

https://huagongshe.com/reaction/2060233

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chlorobenzoyl chlorideHCID 8501—
ReactantEthyl pyrrolidine-3-carboxylateHCID 12896002—
Product1-(4-Chloro-benzoyl)-pyrrolidine-3-carboxylic acid ethyl esterHCID 5932218579%

Reaction Steps

The title compound was prepared according to the method described for Preparation 2 using pyrrolidine-3-carboxylic acid ethyl ester (see Preparation 1) and 4-chloro-benzoyl chloride to afford the title compound as a pale yellow oil (3.02 g, 79%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08278343B2
Source datasetuspto-grants-2012_10
ORD IDord-e9c2fa95e4284a39a76711f80f3879b5
Source noteuspto-grants-2012_10