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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2060274Generated: November 1, 2026

4-Fluoro-4'-hydroxybiphenyl → HCID 59322192, compound

https://huagongshe.com/reaction/2060274

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-4'-hydroxybiphenylHCID 345420—
Reactant3-Iodomethyl-1-(2-methoxy-benzoyl)-pyrrolidine-3-carboxylic acid ethyl esterHCID 59322172—
ProductHCID 59322192HCID 59322192—

Reaction Steps

The title compound was prepared according to the method described for Preparation 29 using 4′-fluoro-biphenyl-4-ol and 3-iodomethyl-1-(2-methoxy-benzoyl)-pyrrolidine-3-carboxylic acid ethyl ester (Preparation 15) to afford the racemate as a white solid (178 mg, 76%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08278343B2
Source datasetuspto-grants-2012_10
ORD IDord-d09025385f8b4ec59f43da9a6253b558
Source noteuspto-grants-2012_10