化工社化工社 化学情報印刷レポート · 研究参考用
1-(2-Ethoxy-benzoyl)-3-iodomethyl-pyrrolidine-3-carboxylic acid ethyl ester → 3-[5-(4-Chloro-phenyl)-pyrazin-2-yloxymethyl]-1-(2-ethoxy-benzoyl)-pyrrolidine-3-carboxylic acid ethyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(2-Ethoxy-benzoyl)-3-iodomethyl-pyrrolidine-3-carboxylic acid ethyl ester | HCID 59322228 | — |
| 反応物 | HCID 178516753 | HCID 178516753 | — |
| 生成物 | 3-[5-(4-Chloro-phenyl)-pyrazin-2-yloxymethyl]-1-(2-ethoxy-benzoyl)-pyrrolidine-3-carboxylic acid ethyl ester | HCID 59322204 | — |
反応手順
The title compound was prepared according to the method described for Preparation 29 using 5-(4-chloro-phenyl)-pyrazin-2-ol (Preparation 25) and 1-(2-ethoxy-benzoyl)-3-iodomethyl-pyrrolidine-3-carboxylic acid ethyl ester (Preparation 16) to afford the racemate as a white solid (86 mg, 30%)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08278343B2 |
| 出典データセット | uspto-grants-2012_10 |
| ORD ID | ord-7c06bcc80f374955a99229bd9a7300ea |
| 出典メモ | uspto-grants-2012_10 |