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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2060302Generated: October 31, 2026

1H-Imidazole-1-propanamine → HCID 25099489, compound

https://huagongshe.com/reaction/2060302

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Imidazole-1-propanamineHCID 78736—
ReactantIndole-5-carboxaldehydeHCID 589040—
ReactantEthyl 2-oxo-3-phenylpropanoateHCID 12292599—
SolventEthanolHCID 702—
ProductHCID 25099489HCID 25099489—

Reaction Conditions

Temperature50 °C

Reaction Steps

3-Imidazol-1-yl-propylamine (1 mmol) and 1H-Indole-5-carbaldehyde (1 mmol) were added to ethanol (5 ml). After 30 min 2-Oxo-3-phenyl-propionic acid ethylester (1 mmol) was added. The reaction was heated to 50° C. and stirred for 24 h. After evaporation of the solvent the residue was purified with chromatographic methods.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08278345B2
Source datasetuspto-grants-2012_10
ORD IDord-38a0307000134d70b177523d014609f0
Source noteuspto-grants-2012_10