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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2060307Generated: November 1, 2026

3,4-Dimethylbenzaldehyde → HCID 57923946, compound

https://huagongshe.com/reaction/2060307

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-DimethylbenzaldehydeHCID 22278—
Reactant1H-Imidazole-1-propanamineHCID 78736—
ReactantHCID 12457675HCID 12457675—
SolventEthanolHCID 702—
ProductHCID 57923946HCID 57923946—

Reaction Conditions

Temperature50 °C

Reaction Steps

3-Imidazol-1-yl-propylamine (1 mmol) and 3,4-Dimethyl-benzaldehyde (1 mmol) were added to ethanol (5 ml). After 30 min 3-(1H-Indol-3-yl)-2-oxo-propionic acid ethyl ester (1 mmol) was added. The reaction was heated to 50° C. and stirred for 24 h. After evaporation of the solvent the residue was purified with chromatographic methods.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08278345B2
Source datasetuspto-grants-2012_10
ORD IDord-feb1ac96ba7b4f47bfe02d4148c64d0b
Source noteuspto-grants-2012_10