Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2060311Generated: November 4, 2026

o-Fluorobenzaldehyde → HCID 57923939, compound

https://huagongshe.com/reaction/2060311

Reaction equation

Participants

RoleNameHCIDCharge
Reactanto-FluorobenzaldehydeHCID 67970—
Reactant1H-Imidazole-1-propanamineHCID 78736—
ReactantHCID 12457675HCID 12457675—
SolventEthanolHCID 702—
ProductHCID 57923939HCID 57923939—

Reaction Conditions

Temperature50 °C

Reaction Steps

3-Imidazol-1-yl-propylamine (1 mmol) and 2-Fluoro-benzaldehyde (1 mmol) were added to ethanol (5 ml). After 30 min 3-(1H-Indol-3-yl)-2-oxo-propionic acid ethyl ester (1 mmol) was added. The reaction was heated to 50° C. and stirred for 24 h. After evaporation of the solvent the residue was purified with chromatographic methods.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08278345B2
Source datasetuspto-grants-2012_10
ORD IDord-bfdeb5f734454e5cb27b019e7b489088
Source noteuspto-grants-2012_10