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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2060313Generated: October 30, 2026

1H-Imidazole-1-propanamine → HCID 57923941, compound

https://huagongshe.com/reaction/2060313

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Imidazole-1-propanamineHCID 78736—
ReactantIndole-5-carboxaldehydeHCID 589040—
ReactantHCID 21480041HCID 21480041—
SolventEthanolHCID 702—
ProductHCID 57923941HCID 57923941—

Reaction Conditions

Temperature50 °C

Reaction Steps

3-Imidazol-1-yl-propylamine (1 mmol) and 1H-Indole-5-carbaldehyde (1 mmol) were added to ethanol (5 ml). After 30 min 3-(4-Hydroxy-phenyl)-2-oxo-propionic acid ethyl ester (1 mmol) was added. The reaction was heated to 50° C. and stirred for 24 h. After evaporation of the solvent the residue was purified with chromatographic methods.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08278345B2
Source datasetuspto-grants-2012_10
ORD IDord-f6f4f3647277457894897a9b2baa0a43
Source noteuspto-grants-2012_10