HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2060320Generated: October 31, 2026
Furfural → 5-Furan-2-yl-3-hydroxy-1-(3-imidazol-1-yl-propyl)-4-pentyl-1,5-dihydro-pyrrol-2-one
https://huagongshe.com/reaction/2060320
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Furfural | HCID 7362 | — |
| Reactant | 1H-Imidazole-1-propanamine | HCID 78736 | — |
| Reactant | Ethyl 2-oxooctanoate | HCID 10888659 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-Furan-2-yl-3-hydroxy-1-(3-imidazol-1-yl-propyl)-4-pentyl-1,5-dihydro-pyrrol-2-one | HCID 57924095 | — |
Reaction Steps
3-Imidazol-1-yl-propylamine (1 mmol) and Furan-2-carbaldehyde (1 mmol) were added to ethanol (5 ml). After 30 min 2-Oxo-octanoic acid ethyl ester (1 mmol) was added. The reaction was heated to 50° C. and stirred for 24 h. After evaporation of the solvent the residue was purified with chromatographic methods.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08278345B2 |
|---|
| Source dataset | uspto-grants-2012_10 |
|---|
| ORD ID | ord-1744b439609d4f2e86b9c88172d0c475 |
|---|
| Source note | uspto-grants-2012_10 |
|---|
