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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2060322Generated: November 2, 2026

o-Fluorobenzaldehyde → HCID 57923893, compound

https://huagongshe.com/reaction/2060322

Reaction equation

Participants

RoleNameHCIDCharge
Reactanto-FluorobenzaldehydeHCID 67970—
Reactant1H-Imidazole-1-propanamineHCID 78736—
ReactantEthyl 2-oxooctanoateHCID 10888659—
SolventEthanolHCID 702—
ProductHCID 57923893HCID 57923893—

Reaction Conditions

Temperature50 °C

Reaction Steps

3-Imidazol-1-yl-propylamine (1 mmol) and 2-Fluoro-benzaldehyde (1 mmol) were added to ethanol (5 ml). After 30 min 2-Oxo-octanoic acid ethyl ester (1 mmol) was added. The reaction was heated to 50° C. and stirred for 24 h. After evaporation of the solvent the residue was purified with chromatographic methods.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08278345B2
Source datasetuspto-grants-2012_10
ORD IDord-b5613c6bfd24474baa698526c342b436
Source noteuspto-grants-2012_10