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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2060327Generated: November 2, 2026

Ethyl 2,4-dioxovalerate → HCID 178467286, compound

https://huagongshe.com/reaction/2060327

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2,4-dioxovalerateHCID 69208—
Reactant8-Hydroxy-2-quinolinecarboxaldehydeHCID 599342—
ReactantHCID 178507353HCID 178507353—
SolventEthanolHCID 702—
ProductHCID 178467286HCID 178467286—

Reaction Conditions

Temperature50 °C

Reaction Steps

1H-Benzoimidazol-5-ylamine (1 mmol) and 8-Hydroxy-quinoline-2-carbaldehyde (1 mmol) were added to ethanol (5 ml). After 30 min 2,4-Dioxo-pentanoic acid ethyl ester (1 mmol) was added. The reaction was heated to 50° C. and stirred for 24 h. After evaporation of the solvent the residue was purified with chromatographic methods.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08278345B2
Source datasetuspto-grants-2012_10
ORD IDord-f39f46842fe2489291e1ea42739f3db0
Source noteuspto-grants-2012_10