HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2060340Generated: October 29, 2026
Benzo(c)(1,2,5)oxadiazole-5-carbaldehyde → HCID 178519909, compound
https://huagongshe.com/reaction/2060340
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzo(c)(1,2,5)oxadiazole-5-carbaldehyde | HCID 2776296 | — |
| Reactant | Ethyl 4-cyclopropyl-2,4-dioxobutanoate | HCID 16779961 | — |
| Reactant | HCID 178507353 | HCID 178507353 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178519909 | HCID 178519909 | — |
Reaction Steps
1H-Benzoimidazol-5-ylamine (1 mmol) and Benzo[1,2,5]oxadiazole-5-carbaldehyde (1 mmol) were added to ethanol (5 ml). After 30 min 4-Cyclopropyl-2,4-dioxo-butyric acid ethyl ester (1 mmol) was added. The reaction was heated to 50° C. and stirred for 24 h. After evaporation of the solvent the residue was purified with chromatographic methods.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08278345B2 |
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| Source dataset | uspto-grants-2012_10 |
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| ORD ID | ord-aece5d07023d46b69e9d586dc00aad8f |
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| Source note | uspto-grants-2012_10 |
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