HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-aminoisobutyrate hydrochloride → 2-[(1-Chloro-4-hydroxy-6-isopropoxy-isoquinoline-3-carbonyl)-amino]-2-methyl-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-aminoisobutyrate hydrochloride | HCID 13258034 | — |
| Reactant | 1-Chloro-4-hydroxy-6-isopropoxy-isoquinoline-3-carboxylic acid | HCID 54242250 | — |
| Product | 2-[(1-Chloro-4-hydroxy-6-isopropoxy-isoquinoline-3-carbonyl)-amino]-2-methyl-propionic acid | HCID 11372033 | — |
Reaction Steps
Prepared in analogy to Example A-1 a) and b) from 1-chloro-4-hydroxy-6-isopropoxy-isoquinoline-3-carboxylic acid (can be obtained according to U.S. Pat. No. 6,093,730, October 1998, Weidmann et al.) and 2-amino-2-methyl-propionic acid methyl ester hydrochloride; MS-(+)-ion: M+1=367.0 amu.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08278325B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-cd2611b4cda148c6a2e6f6a9562bb94a |
| Source note | uspto-grants-2012_10 |