HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycine → HCID 86014531, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycine | HCID 750 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | HCID 86595473 | HCID 86595473 | — |
| Product | HCID 86014531 | HCID 86014531 | — |
Reaction Steps
216 mg of 1-bromo-4-hydroxy-6-phenylsulfanyl-isoquinoline-3-carboxylic acid butyl ester (0.5 mmol) from Example D-2a) were reacted with glycine and sodium methylate analogously to Example D-1 g). 194 mg of the title compound were obtained; 1H NMR (DMSO-d6): δ=9.17 (t, 1H), 8.12 (d, 1H), 7.51 to 7.78 (m, 7H), 4.00 (d, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08278325B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-b3d3445998c645cd8e634e76bd5dec25 |
| Source note | uspto-grants-2012_10 |