HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Dimethyl-1,3-propanediamine → 2H-Cyclopenta[c]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Dimethyl-1,3-propanediamine | HCID 7993 | — |
| Reactant | Baldrinal | HCID 159846 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 2H-Cyclopenta[c]pyridine | HCID 15559852 | — |
Reaction Steps
Baldrinal (2) (12.8 mg) was reacted with 3-(dimethylamino)-1-propylamine (22.5 mg) in 2 ml of chloroform. After stirring for 10 minutes at room temperature, the solution turned red and all the baldrinal was reacted. Compound (9) was separated using column chromatography with silica using 50:1 CHCl3:MeOH solvent system and 2.2 mg of product was collected.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08278451B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-d4409216d16e4af99c6f720fdb4c6088 |
| Source note | uspto-grants-2012_10 |