6-Chloro-3-pyridinecarbonitrile → 6-(5-Methylnaphthalen-1-yloxy)nicotinonitrile

HRID 2060859Notes

Reaction equation

HRID 2060859 reaction equation
[CH3:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[C:7]2[OH:12].Cl[C:14]1[CH:21]=[CH:20][C:17]([C:18]#[N:19])=[CH:16][N:15]=1>>[CH3:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[C:7]2[O:12][C:14]1[CH:21]=[CH:20][C:17]([C:18]#[N:19])=[CH:16][N:15]=1

Participants

3

Reactant 2

HCID 51520946-Chloro-3-pyridinecarbonitrileHCID 113556405-Methylnaphthalen-1-ol

Product 1

HCID 594013126-(5-Methylnaphthalen-1-yloxy)nicotinonitrile

Procedure

Using the procedure outlined in Preparation 15, 5-methylnaphthalen-1-ol and 6-chloronicotinonitrile were converted to the title compound: RT=3.90 min; m/z (ES+)=261.1 [M+H]+.

Sources & evidence

ORD record
ord-9eb75e51197d4278b85308ebf7aebfc8
Source dataset
uspto-grants-2012_10
Patent number
US08278442B2

Reaction notes

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