6-Chloro-3-pyridinecarbonitrile → HCID 59401349, compound

HRID 2060866Notes

Reaction equation

HRID 2060866 reaction equation
[OH:1][CH2:2][C:3]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:4]=1[CH:5]=[CH:6][CH:7]=[C:8]2[OH:13].Cl[C:15]1[CH:22]=[CH:21][C:18]([C:19]#[N:20])=[CH:17][N:16]=1>>[OH:1][CH2:2][C:3]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:4]=1[CH:5]=[CH:6][CH:7]=[C:8]2[O:13][C:15]1[CH:22]=[CH:21][C:18]([C:19]#[N:20])=[CH:17][N:16]=1

Participants

3

Reactant 2

HCID 51520946-Chloro-3-pyridinecarbonitrileHCID 57979480HCID 57979480, compound

Product 1

HCID 59401349HCID 59401349, compound

Procedure

Using the procedure outlined in Preparation 15, 5-hydroxymethylnaphthalen-1-ol (Preparation 32) and 6-chloronicotinonitrile were converted to the title compound: RT=3.17 min; m/z (ES+)=277.1 [M+H]+.

Sources & evidence

ORD record
ord-8059c07751a94e15add25ebc96c457f5
Source dataset
uspto-grants-2012_10
Patent number
US08278442B2

Reaction notes

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