4-Hydroxy-1-naphthaldehyde → HCID 59401356, compound

HRID 2060889Notes

Reaction equation

HRID 2060889 reaction equation
[OH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([CH:12]=[O:13])=[CH:4][CH:3]=1.[F:14][C:15]1[CH:16]=[C:17]([CH:20]=[CH:21][C:22]=1F)[C:18]#[N:19]>>[F:14][C:15]1[CH:16]=[C:17]([CH:20]=[CH:21][C:22]=1[O:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([CH:12]=[O:13])=[CH:4][CH:3]=1)[C:18]#[N:19]

Participants

3

Reactant 2

HCID 3442904-Hydroxy-1-naphthaldehydeHCID 5872033,4-Difluorobenzonitrile

Product 1

HCID 59401356HCID 59401356, compound

Procedure

Using the procedure outlined in Preparation 82, 4-hydroxynaphthaldehyde and 3,4-difluorobenzonitrile were converted to the title compound: RT=3.90 min; m/z (ES+)=292.1 [M+H]+.

Sources & evidence

ORD record
ord-82cb122f3b98431889ca7be405154f25
Source dataset
uspto-grants-2012_10
Patent number
US08278442B2

Reaction notes

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