Indole → HCID 59238891, compound

Participants

Reaction Steps

The title compound was prepared in a manner analogous to Example 28 except the starting indole is 5,7-diBOC-2,10-dichloro-6-hydroxyindolo[2,3-b]carbazole and the reagent is (S)-(+)-1-(tert-butoxycarbonyl)-2-pyrrolidinemethanol. 1H-NMR (400 MHz, CD3OD) δ ppm 8.46 (s, 1H), 8.11 (d, J=2.4 Hz, 2H), 7.41 (d, J=8.4 Hz, 2H), 7.30 (dd, J=8.4, 2.4 Hz, 2H), 4.33 (dd, J=10.0, 3.2 Hz, 1H), 4.11 (dd, J=10.0, 8.4 Hz, 1H), 3.91-3.82 (m, 1H), 3.16 (t, J=7.2 Hz, 2H), 2.16-2.05 (m, 1H), 2.03-1.84 (m, 2H), 1.72-1.62 (m, 1H); MS (ESI) m/z 422.2 (M−H)−; MS (ESI) m/z 424.0 (M+H)+

Provenance & Evidence