HCID 67309471, compound → HCID 67310805, compound

Participants

Reaction Steps

1-(3-(Benzyloxycarbonylamino)-3-methylbutyl)-4,4-difluoro-1-methylpiperidinium chloride (1.78 g, 4.49 mmol) was dissolved into water (100 mL) and 10% Pd/C (300 mg) was added to the flask. It was sealed and degassed with vacuum and flushed with hydrogen from a balloon (3 times). The reaction was stirred at room temperature for 17 h. The suspension was filtered through a pad of Celite® and the solid was washed with water (2×50 mL). The filtrate was concentrated to a viscous oil which became a white foam after being dried under high vacuum (1.30 g, quant). LRMS (ESI+) for C11H23F2N2+ (221.1); Found: 221 (M+).

Provenance & Evidence