HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxybenzaldehyde → 4-((2-Fluorophenyl)methoxy)benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxybenzaldehyde | HCID 126 | — |
| Reactant | Benzene, 1-(chloromethyl)-2-fluoro- | HCID 9580 | — |
| Product | 4-((2-Fluorophenyl)methoxy)benzaldehyde | HCID 702717 | — |
Reaction Steps
4-(2-Fluorobenzyloxy)benzaldehyde is prepared by alkylation of 4-hydroxybenzaldehyde (0.39 g) with 2-fluorobenzyl chloride by following the same procedure of Example 1, but using three different phase transfer catalysts.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08278485B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-4a365c78fea3458392c3f87ebf2bc0e5 |
| Source note | uspto-grants-2012_10 |