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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2061152Generated: October 25, 2026

(S)-2-[4-(2-fluorobenzyloxy)benzylideneamino]propanamide → Priralfinamide

https://huagongshe.com/reaction/2061152

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-2-[4-(2-fluorobenzyloxy)benzylideneamino]propanamideHCID 23659931—
Reactant(S)-2-((3-(2-Fluorobenzyl)-4-((2-fluorobenzyl)oxy)benzyl)amino)propanamideHCID 57745326—
ProductPriralfinamideHCID 574520793%

Reaction Steps

(S)-2-[4-(2-Fluorobenzyloxy)benzylamino]propanamide is prepared in a 93% yield from (S)-2-[4-(2-fluorobenzyloxy)benzylideneamino]propanamide by following the same procedure of Example 8, step b). The content of (S)-2-[3-(2-fluorobenzyl)-4-(2-fluorobenzyloxy)-benzylamino]propanamide is 0.02% by weight determined by HPLC (see Example 17B).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08278485B2
Source datasetuspto-grants-2012_10
ORD IDord-d9ca47efd66041b4b520a3c0dda7f127
Source noteuspto-grants-2012_10