HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 59853912, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Propane, 1-iodo-2,2-dimethyl- | HCID 84953 | — |
| Reactant | HCID 68420335 | HCID 68420335 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 59853912 | HCID 59853912 | — |
Reaction Conditions
| Temperature | 120 °C |
|---|
Reaction Steps
150 mg (0.406 mmol) of 2-[4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-piperidinyl]-2-oxoethanamine hydrochloride, 80.5 mg (0.406 mmol) of 2,2-dimethyl-1-iodopropane and 84.3 mg (0.610 mmol) of potassium carbonate were dissolved in 1 ml of N,N-dimethylformamide, and the obtained solution was stirred at 120° C. overnight. The product was purified by the silica gel chromatography (hexane:ethyl acetate=9:1 to 2:3) to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08278329B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-fef8bbc1cd474a64b5cc30ad5359642a |
| Source note | uspto-grants-2012_10 |