TBAF tetrahydrofuran → HCID 59853899, compound

Participants

Reaction Steps

113 mg (0.197 mmol) of N-[2-(t-butylamino)-1-({[t-butyl(dimethyl)-silyl]oxy}methyl)-2-oxoethyl]-4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-piperidinecarboxamide was dissolved in 3 ml of tetrahydrofuran. 0.22 ml of 1 M tetrabutylammonium fluoride/tetrahydrofuran solution was added to the obtained solution, and they were stirred for 30 minutes. After the purification by the silica gel chromatography (hexane:ethyl acetate=9:1 to 3:2), the title compound was obtained.

Provenance & Evidence