Water → HCID 86648108, compound

Participants

Reaction Steps

A 300-mL reaction vessel was charged with 31.85 g (purity: 47%, 48.0 mmol) of sodium cyclohexylcarbamic acid-2,2-difluoroethylsulfonate, 15.8 g (52.9 mmol) of triphenylsulfonium chloride, 170 g of water and 30 g of chloroform. The resulting solution was stirred for 4 hours at room temperature and separated into two phases. The aqueous phase was extracted with chloroform. The thus-obtained organic phases were combined together. The combined organic phase faction was washed six times with water, subjected to concentration, washed three times with diisopropyl ether, and then, dried, thereby yielding 24.5 g of triphenylsulfonium cyclohexylcarbamic acid-2,2-difluoroethylsulfonate as a target product. The purity of the product was 76%; and the yield of the product was 70%.

Provenance & Evidence