HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dibromobutane → 1-(Toluene-4-sulfonyl)cyclopentanecarbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dibromobutane | HCID 8056 | — |
| Reactant | Tosylacetonitrile | HCID 79776 | — |
| Catalyst | Benzyl triethylammonium chloride | HCID 66133 | — |
| Product | 1-(Toluene-4-sulfonyl)cyclopentanecarbonitrile | HCID 43419786 | 84% |
Reaction Steps
Similarly to Example 1 paragraph (a), by reaction of 2 g (10.2 mmol) of (toluene-4-sulfonyl)-acetonitrile with 1.35 ml (11.3 mmol) of 1,4-dibromobutane, 50 ml of aqueous soda solution, 233 mg (1 mmol) of benzyltriethylammonium chloride. 2.14 g of 1-(toluene-4-sulfonyl)cyclopentanecarbonitrile is obtained in the form of a brown powder. (Yield=84%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08283378B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-1cf7b5ad78c34da5ba4b052e3ad64577 |
| Source note | uspto-grants-2012_10 |