HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminium lithium hydride → C-[1-(toluene-4-sulfonyl)-cyclopentyl]-methylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | 1-(Toluene-4-sulfonyl)cyclopentanecarbonitrile | HCID 43419786 | — |
| Product | C-[1-(toluene-4-sulfonyl)-cyclopentyl]-methylamine | HCID 68630538 | 36% |
Reaction Steps
Similarly to Example 1(b), by reaction of 1.1 g (4.4 mmol) of 1-(toluene-4-sulfonyl)-cyclopentanecarbonitrile with 200 mg of aluminum lithium hydride. 400 mg of C-[1-(toluene-4-sulfonyl)-cyclopentyl]-methylamine is obtained in the form of an orange solid. (Yield=36%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08283378B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-e6bcfbf5fa1344ada7054e31bd44f289 |
| Source note | uspto-grants-2012_10 |