2,6-Diisopropylphenyl isocyanate → HCID 25225483, compound

HRID 2061648Notes

Reaction equation

HRID 2061648 reaction equation
[C:1]1([S:7]([C:10]2([CH2:19][NH2:20])[CH2:18][C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[CH2:11]2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[N:21]([C:24]1[C:29]([CH:30]([CH3:32])[CH3:31])=[CH:28][CH:27]=[CH:26][C:25]=1[CH:33]([CH3:35])[CH3:34])=[C:22]=[O:23]>>[C:1]1([S:7]([C:10]2([CH2:19][NH:20][C:22]([NH:21][C:24]3[C:25]([CH:33]([CH3:34])[CH3:35])=[CH:26][CH:27]=[CH:28][C:29]=3[CH:30]([CH3:32])[CH3:31])=[O:23])[CH2:11][C:12]3[C:17](=[CH:16][CH:15]=[CH:14][CH:13]=3)[CH2:18]2)(=[O:9])=[O:8])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 922592,6-Diisopropylphenyl isocyanateHCID 68631578HCID 68631578, compound

Product 1

HCID 25225483HCID 25225483, compoundYield 36%

Procedure

Similarly to Example 1(c), by reaction of 168 mg (0.6 mmol) of C-(2-benzenesulfonyl-indan-2-yl)-methylamine with 131 mg (0.64 mmol) of 2-isocyanato-1,3-diisopropyl-benzene. 106 mg of 1-(2-benzenesulfonyl-indan-2-ylmethyl)-3-(2,6-diisopropyl-phenyl)-urea is obtained in the form of a white solid. (Yield=36%).

Sources & evidence

ORD record
ord-5cd6b96e4f634b9aa44e5e5aac4e9eff
Source dataset
uspto-grants-2012_10
Patent number
US08283378B2

Reaction notes

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